Service
Term Stim™ is a comprehensive reproductive-physiology investigation designed to analyze the integrity of the ovarian cycle as a coordinated system – from follicular development through ovulation and luteal function – in order to assist physicians in managing difficult reproductive cases, including poor egg quality and failed frozen embryo transfers.
Term Stim™ is delivered in collaboration with the ordering physician, using a research-grade Translational Fertility EMR built to analyze patient data in the context of this new physiology.
Term Stim™ is delivered with a specialized EMR developed by Translational Fertility from scratch to assist physicians in creating and executing a treatment strategy for patients who have already failed ovarian stimulation due to poor egg quality. It is not only a research tool, but is also capable providing step-by-step reproductive physiology recommendations using proprietary knowledge base and the totality of the patient’s history, diagnostic cycle, and current cycle data.
Limited Use of AI
In medicine, AI is very successful at searching for and applying a template that worked for a similar patient. But in cases of poor egg quality, this approach is rarely fruitful, since each case is unique. Therefore, in Term Stim™, we use AI only to help track relevant variables and identify subtle trends in a patient’s data that might otherwise be overlooked. However, all validation, interpretation, and recommendations remain entirely human – grounded in research, experience, and expertise.
Our Custom EMR Design for Research and Collaboration
Diagnostic Cycle
For routine IVF, granular cycle data is rarely actionable. For complex cases, however, a detailed physiologic study is essential. Therefore every Term Stim™ engagement begins with a diagnostic cycle – about one month of structured monitoring – to map the patient’s reproductive dynamics, identify potential contributors to poor egg quality, and generate guidance for the subsequent treatment cycle.
For example, you may find that a patient’s follicles begin to luteinize at 16 mm (not 18 mm), with progesterone rising from 0.1 ng/mL to 0.4 ng/mL. This points to the need for a pre-emptive trigger and helps determine whether premature luteinization affects one follicle or the entire cohort.
It also gives an opportunity to test and quantify the patient’s response to medications planned for treatment. For instance, we confirm whether FSH kinetics follow the expected compounding profile; if not, we help you define dose and timing adjustments.
When appropriate, the diagnostic cycle can transition directly into treatment – for example, if an unexpectedly well-synchronized cohort is observed after an LH surge.
Treatment Cycle
The board: A structured case board (timeline + variable panes) that shows the whole case at a glance.
The pieces: Growth tempo, cohort synchrony, historic and current FSH, P4, E2 and LH trends , micro P4 drift, E2–size concordance, prior cycle kinetics, looks backs, medication states, etc.
The rules: Latest reproductive physiology, proprietary and patent pending
algorithms, protocol preferences, evidence weighting etc.
Briefs: Step-by-step briefs, based on evidence driven synthesis, that you can review in under a minute.
For essential data entry you and staff members can use our mobile app with very intuitive interface.
The Term Stim™ platform enables physicians to deliver previously unattainable level of care to their patients as a premium service.
Evidence driven synthesis. Case specific briefs.
Disclaimer: The information provided is not intended as medical advice. Translational Fertility LLC offers consulting and advisory services in reproductive physiology exclusively to participating physicians, who are fully licensed in their respective jurisdictions and who retain full clinical discretion and control over the diagnosis, care, and treatment of their patients.