Patients

As Long as there are Eggs, there is Hope

Each poor egg quality case is unique and, in effect, a research project focused on a single patient. Term Stim™ adds reproductive-physiology research expertise and tools to complement your physician’s clinical expertise, deepen the understanding of your case, and help create and carry out a fully customized treatment plan.

Poor Egg Quality

When embryos fail to develop in vitro (in a Petri dish) or develop into chromosomally abnormal blastocysts, “poor egg quality” is usually declared. Importantly, poor egg quality is not a diagnosis but an observation based on your physician’s experience with your IVF cycle, and it does not automatically mean that all eggs in your ovaries are of poor quality.

Until recently, we believed that egg quality is always intrinsic to the female. Yet, today we know that egg quality can be greatly influenced by ovarian stimulation. The new ovulation paradigm has highlighted potential new entry points for controlling egg quality. Each case of poor egg quality is unique, and we approach it with an open mind to any possibility. 

Term Stim™

Term Stim™ is a specialized reproductive-physiology service provided by your physician in collaboration with Texas-based Translational Fertility LLC. Its purpose is to achieve a deeper and more granular understanding of your individual reproductive physiology to help improve egg quality. The service is supported by Translational Fertility ’s reproductive-physiology experts using a software platform designed specifically for the research and management of poor–egg–quality cases.

What to Expect

  1. First, at your physician’s request, Translational Fertility will determine whether you are a candidate for the Term Stim™ service. If your case is not accepted, no report will be issued and you will not be charged.
  2. The Term Stim™ process begins with a Diagnostic Cycle, during which your natural menstrual cycle is studied over about one month to reveal aspects of your unique ovarian physiology that are important for customizing your treatment cycle.
  3. The information collected during the Diagnostic Cycle is then analyzed together with your previous IVF responses, your reproductive history, and other contributing factors. The goal is to understand your ovarian physiology in its entirety.
  4. Using this comprehensive profile, your physician designs a personalized ovarian stimulation plan to support egg development in a way that is expected to improve egg quality and ultimately increase the likelihood of achieving a successful pregnancy and birth.
  5. During the treatment cycle, whenever new information about your response becomes available, it is reviewed by Translational Fertility and your physician to determine whether any adjustments are needed.

Involvement and Compliance

 Term Stim™ requires greater engagement and strict adherence. You’ll need to be available, patient, and prepared for more appointments and to follow your provider’s recommendations closely.

Setting Expectations

In poor egg quality cases, outcomes are uncertain, and improvement cannot be predicted or quantified because each case is unique. Our promise is honest, disciplined, evidence-driven research with individualized steps that may improve your odds but do not guarantee success. In some cases, poor egg quality is intrinsic and cannot be changed. But the only way to find out is to try.

Finding Provider

You can reach us first, and we will locate a physician in your area who is currently working with Translational Fertility or is interested to become our partner. At this time we work with physicians in the United States, Europe and South America.  

Availability of Service

At this time, most of our work cannot be automated, and we can assist physicians with only a very limited number of cases at any given time. As a result, a waiting period should be expected. We also accept cases only after poor egg quality has been validated and only when, in our judgment, there is a meaningful chance of improving the outcome.

Case Acceptance

On your physician’s order, we will accept your case for preliminary review (free). We will inform your physician within about one week whether we accept or decline working on the case.

Direct Contact

Please note that we communicate directly about your diagnosis and treatment ONLY with physicians and not patients. However, you may contact our office to help you find a participating physician in your area and sometime we may have a question that we need you to clarify.   

Disclaimer: The information provided is not intended as medical advice. Translational Fertility LLC offers consulting and advisory services in reproductive physiology exclusively to participating physicians, who are fully licensed in their respective jurisdictions and who retain full clinical discretion and control over the diagnosis, care, and treatment of their patients.