Progymax™
REPURPOSING OF PROGESTERONE FOR TRIGERRING OVULATION
US Patent Issued. International pending. Co-Invented with Michael P. Diamond, MD of Augusta University
The Problem: Artificial Luteal Phase is Suboptimal
Discovery
Prediction and Protocol
Case report
Case report
Potential Benefits
Patent
Publications
Progesterone is a physiological trigger of ovulatory gonadotropins. Dozortsev D, Pellicer A, Diamond MP. Fertil Steril. 2020 May;113(5):923-924. doi: 10.1016/j.fertnstert.2019.12.024. Epub 2020 Feb 12. PMID: 32059812
Luteinizing hormone-independent rise of progesterone as the physiological trigger of the ovulatory gonadotropins surge in the human. Dozortsev DI, Diamond MP. Fertil Steril. 2020 Aug;114(2):191-199. doi: 10.1016/j.fertnstert.2020.06.016. PMID: 32741458
Ovulation and birth after administration of progesterone trigger-two case reports. Villar L, Tralik B, Diamond MP, Allon M, Maldonado I, Dozortsev DI. J Assist Reprod Genet. 2023 May;40(5):1037-1044. doi: 10.1007/s10815-023-02750-x. Epub 2023 Feb 20. PMID: 36808579